Key challenges and potential solutions for eliminating bottlenecks and optimizing biopharma downstream processes

Finding efficiencies across downstream processing steps and cost-effectively aligning the productivity of downstream production with upstream yields require complex analysis and optimisation.

This presentation elaborates on the key aspects of downstream processing, looking at different areas where improvements by new techniques and new technologies could be made, from current process chromatography technologies, new powder and liquid handling strategies to raw material data analysis.

This presentation was given during Bioprocessing Summit Virtual, March 16–17, 2021.

Presented by:

Willie Hesselink

Willie Hesselink is a Senior Technical Application Project Manager at Avantor. Prior to this role, he was a R&D Manager at Avantor Performance Materials in Deventer, Netherlands.

Willie brings over 20 years of industrial expertise in the research and development of raw materials and excipients used in the different steps of biopharmaceutical processes. In his current role working within Avantor's biopharma production business unit, he has lead many process optimization and cost reduction projects in collaboration with customers. Willie holds a B.Sc. in analytical chemistry from the Saxion University of Applied Sciences in Enschede, Netherlands.