Downstream Process Enhancement for Monoclonal Antibody Manufacturing
Advancing the molecule to production
Buffer Management
Overwhelmed with increased buffer demand for buffer manufacturing capacity? Trust Avantor's customized solutions to save costs, resources, and facility space.
Depth Filtration
Not every system is the same, so choose the solution that fits in every system. Our experts know how to build agnostic solutions that meet your unique specifications in sterile depth filtration.
Detergent-based Viral Inactivation
Virus clearance may be one of the most important process steps to ensure product safety. What you need: an efficient inactivation method to alleviate the virus/impurity clearance burden for subsequent process steps. And this is not enough: consider environmental concerns and regulatory requirements - minimize the challenge.
Chromatography
Remove bottlenecks in your purification process. We offer solutions with fewer steps and increased protein yield.
Viral Clearance
Do you want to mitigate the risk running with manual adjustments in your viral clearance process? We can build your unique automated system to secure your process.
UF/DF
Without quality flow filtration, your purification process remains critical. From lab to pilot stage all the way to full-scale manufacturing or continuous processing, you need the expertise and the agnostic, differentiated solutions.
Viral Filtration
While viral inactivation using detergents or low pH delivers high levels of viral clearance, additional viral filtration methods such as TFF or dead-end filtration need to apply to achieve virological safety of the biologic.